MetXtra™ Enzyme Discovery
What's in for you?
- Enzymes with new activities, novel features and Freedom to Operate (FTO)
- Novel enzymes tailored to your specific reaction and application
- Vast, proprietary sequence diversity enhanced by AI-driven enzyme design
- Accelerated selection through targeted in-silico screening and application-relevant testing
- The choice between fully customized discovery projects and ready-to-test bespoke enzyme panels
- The de-risking and acceleration of enzyme development utilizes scalable, industrial production strains.
Discovering new enzymes for application
Identify novel enzymes specifically tailored to your challenge and designed to perform effectively in real-world applications. Our unique in-silico platform, MetXtra™, enables us to discover and develop the right enzymes for your specific needs. MetXtra™ consist of three modules:
- MetXtra™ database is unique in that it expands the known sequence space by adding more than 99 % novel sequences and associated functionality. It is a continuously growing metagenomic database built from Nagoya-compliant sources, with no benefit-sharing obligations. The database covers a diverse range of habitats, including soils, aquatic environments, and wetlands, and features the largest digital database of genetic resources from the Norwegian deep sea and marine environments.
- MetXtra™ design uses AI-driven enzyme design to create novel enzymes beyond the naturally occurring sequence space. It continuously benefits from advances and training based on the MetXtra™ database, enabling the design of increasingly diverse and functional enzymes.
- MetXtra™ discover identifies enzymes tailored to your application by combining technologies such as sequence and structural bioinformatics with AI approaches to achieve the optimal solution.
The MetXtra™ platform combines a large database of proprietary metagenomes with AI-designed enzymes and an in-silico workflow for the targeted selection of the best enzymes for a given application. It uncovers new, high-value enzyme candidates.
Access the MetXtra™ platform
Unlocking the right biocatalyst starts with a clear understanding of the chemistry you need to drive. There are two ways to benefit from our platform, depending on your specific challenge, starting point, and the capabilities you already have in place.
1. Custom enzyme discovery project
In a tailor-made solution project, our enzyme technologists work closely with you to understand and define the specific challenge in detail. Whether a target enzyme is already available or the goal is to identify an enzyme capable of catalyzing a desired reaction, we develop a customized discovery solution to address your individual need.
- Each project can leverage our full technology toolbox.
- Semi-automated, multi-parameter experimental evaluation ensures high accuracy while assessing application-relevant properties.
- Customers can also benefit from the evaluation of novel enzymes in our diverse microbial production platforms.
2. Bespoke enzyme panels
We run MetXtra™ enzyme discovery specifically based on your query sequence or target biotransformation. 48 discovered enzymes will be produced in duplicates in E. coli.
We supply you with the 96‑well plate containing the produced enzyme panel, allowing you to test the enzymes on your relevant substrates directly.
Our streamlined, step-by-step approach ensures every enzyme panel is built with purpose, from defining the desired conversion, to in-silico selection, to rapid gene expression and plate-ready delivery.
Whether you’re exploring novel reaction space or validating known sequences, this workflow gives you clarity, speed and confidence in selecting the optimal biocatalyst.
