From Target Definition to Validated Enzyme Candidates in Less Time
From Target Definition to Validated Enzyme Candidates in Less Time
Accelerate enzyme discovery with the MetXtra™ technology platform and pave the way for your breakthrough in industrial biocatalysis
One of the biggest challenges in enzyme development is finding an enzyme that delivers the required activity, stability, and manufacturability under industrial conditions. To address these challenges, our customers get access to MetXtra™, a technology platform that combines multiple advanced technologies in one discovery workflow.
The MetXtra™ technology platform helps
- to identify high-performing enzyme candidates,
- develop novel enzyme solutions,
- and generate IP or FTO
by combining proprietary metagenomic resources, advanced bioinformatics and AI-driven sequence design.
Whether you are developing enzymes for food, life science or industrial applications, MetXtra™ provides a faster route from target definition to validated enzyme candidates.
Explore enzyme diversity beyond natural sequence space
Traditional enzyme discovery is limited to known biological diversity whereas MetXtra™ expands available sequence space dramatically.
Our platform combines:
- A proprietary, Nagoya-compliant metagenomic sequence database built from the combined resources of BRAINBiocatalysts
- AI-assisted enzyme design to create novelty beyond naturally occurring sequence space
- Advanced sequence and structural bioinformatics to identify the most promising enzyme candidates
This integrated approach increases the likelihood of finding enzymes with the functionality, selectivity and performance required for demanding industrial processes.
Tailored enzyme identification for your specific application
Every application has unique performance requirements. Rather than screening large numbers of enzymes randomly, we use computational analysis and AI-supported workflows to identify candidates that match your target specifications, helping reduce development time and experimental effort.
MetXtra™ provides a competitive advantage to projects:
- Enable novel biocatalytic reactions
- Build IP or secure FTO
- Improve enzyme performance, stability or selectivity
- Development of proprietary enzyme portfolios
“MetXtra™ gives our customers access to a comprehensive database of previously undiscovered enzymes. Combined with advanced bioinformatics, we can rapidly identify promising enzyme candidates for specific applications and help customers build a competitive advantage.
An integrated path from discovery to manufacturing
Identification of an enzyme is only the beginning. Unlike standalone services, MetXtra™ is fully integrated into BRAINBiocatalysts' end-to-end development capabilities, allowing successful candidates to progress seamlessly towards enzyme manufacturing.
Our integrated enzyme development services include:
- Enzyme engineering and optimization
- Microbial production strain development
- Bioprocess development and scale-up
- Fermentation and commercial manufacturing
Working with a single partner throughout development reduces technology transfer risks and accelerates your path to market.
Why choose BRAINBiocatalysts?
- Access to proprietary, unexplored enzyme diversity
- AI-supported enzyme discovery and design
- Application-driven candidate selection
- Reduced enzyme development timelines
- Seamless progression from discovery to commercial production
- One integrated partner across the complete enzyme value chain
How we found an alternative genome-editing platform for engineering industrial strains
This case study shows how we took a holistic approach and combined technologies to provide a more efficient enzyme tailored to the needs of a specific industrial application.
Side streams can be transformed into innovative products: An example from the wine industry
Accelerate enzyme discovery with the MetXtra™ technology platform and pave the way for your breakthrough in industrial biocatalysis
It can be difficult to produce CRISPR nucleases for use as RNPs. This case study demonstrates how we found a solution.
Finding the right enzyme quickly with our directed enzyme panels.
When every stage of enzyme development is connected, innovation moves faster, risks are reduced, and better outcomes become possible.
An enzyme engineered version of BRAIN Biotech´s CRISPR-BMC with superior properties in yeasts accelerates development of high-performance strains.
Quickly assess whether Aspergillus niger is the right production host
